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glycoprotein IIb/IIIa antagonists on glycoprotein IIb/IIIa

Sydney, NSW, Australia Correspondence C. P. Juergens, Cardiology Department, Liverpool Hospital, Liverpool, NSW, Australia. Email: [email protected] ORIGINAL RESEARCH ARTICLE A randomized trial assessing the impact of three different glycoprotein IIb/IIIa antagonists on glycoprotein IIb/IIIa

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The platelet membrane glycoproteins are integrins (α and β subunits) that are found on virtually all cells. 6The glycoprotein IIb/IIIa, an integrin (αIIb/β3 dimer) present on platelet surfaces, is a receptor for fibrinogen, fibronectin, vitronectin, von Willebrand factor, and thrombospondin.It mediates aggregation, adhesion, and spreading of platelets.